Research Use Only • Not for Human Use

What It’s Designed to Help With (Research Context)

• Supports lipolysis (fat breakdown) without activating growth hormone pathways.

• May reduce lipogenesis (new fat formation) in adipose tissue.

• Investigated for body composition optimization and metabolic regulation.

• Explored for cartilage repair and joint‑related research applications.

• Does not elevate IGF‑1 or affect insulin sensitivity in studies.

  
  

How It Works (Mechanism of Action)

Derived from the C‑terminal fragment of human growth hormone (hGH 176–191).

Activates beta‑3 adrenergic receptors in adipocytes, restoring lipolytic sensitivity.

Stimulates the cAMP → PKA → HSL pathway to mobilize stored triglycerides.

Inhibits acetyl‑CoA carboxylase (ACC), reducing new fat synthesis.

Selectively targets fat metabolism without growth‑promoting or diabetogenic effects.